Cancer and Tumor Review

A multi-institution international team led by researchers at Baylor College of Medicine has developed a new strategy to overcome one of the main obstacles in the treatment of brain cancer -- access to the tumor. Under the influence of cancer, the blood-brain barrier diverts immune T cells that attempt to enter the brain to fight the tumor. The new discovery, published in the journal Nature, decodes the molecular cause of this immune escape mechanism and engineers T cells with a first-in-class molecule called Homing System that enables the T cells to cross the impervious cancer blood-brain barrier to effectively fight tumors. Read More Read more about A 'homing system' targets therapeutic T-cells to brain cancer